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AMIC® - Autologous Matrix Induced Chondrogenesis

AMIC® is an innovative biological technique for the treatment of cartilage damage . The unique technique uses the body's own healing abilities in order to treat focal chondral and osteochondral lesions which are larger than 1-2 cm2.

The AMIC® technique combines microfracturing with the application of Chondro-Gide®, a porcine collagen typeI/III bilayer matrix. Through microfracturing,multipotent mesenchymal progenitor cells migrate from the subchondral boneinto the defect. The resulting super clot isstabilisedby the Chondro-Gide® matrix which covers the defect. The natural scaffold of the matrix protects the progenitor cells within a «biological chamber» and stimulates their differentiation to form mostly  hyaline-like cartilaginous repair  tissue.

 

Indications

  • Chondral & osteochondral lesions grade III-IV  (Outerbridge classification)
  • Osteochondral defects in conjuction with bone-grafting
  • Focal, traumatic defects
  • Defect size  2.0-8.0 cm2
  • Patients aged between 18-55 years

 

Surgical technique


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Advantages

  • Minimally-invasive, single step procedure
  • No cultivation of chondrocytes required
  • Treatment of larger cartilage defects unsuitable for microfracture (> 2 cm2)
  • Simple surgical technique
  • Verified improvement of clinical function, high patient satisfaction and pain reduction
  • Over5 years of clinical experience
  • Ad hoc usage and off-the shelf supply of Chondro-Gide®
  • Cost effective

Further information about Chondro-Gide® and AMIC® is available from your Geistlich Surgery representative.

Contact

 


AMIC® in the knee



AMIC® in the talus


Further information

AMIC in the knee
Brochure
Patient Information

Brochure (Polish)
Brochure (Russian)

DVD | Surgical Technique
Download for mobile terminal devices (e.g. iPhone)

AMIC im Knie (German)
AMIC in the Knee (English)
AMIC nel ginocchio (Italiano)
AMIC du genou (Français)




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