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Periodontal Treatment

Scientific background

Periodontal disease is characterised by the destruction of periodontal tissue. If non-surgical, Phase I treatment such as patient education, plaque control, scaling and root planing fails, further surgical solutions are required.

The use of biomaterials for guided tissue regeneration (GTR) is more effective than open flap debridement alone in resolving periodontal defects1. During this procedure the defect is filled with the natural bone substitute Geistlich Bio-Oss® (Collagen) and covered with the collagen membrane Geistlich Bio-Gide® (Perio).

Natural bone substitute should:

Collagen barrier membranes should:

Periodontal treatment - Decision tree
The treatment plan outlines a possible clinical methodology (adopted from Newman, Lindhe, Rateitschak2-4).

Higher attachment gain with Geistlich Bio-Oss® and Geistlich Bio-Gide® Perio

The use of a Geistlich bone substitute material together with native collagen membrane Geistlich Bio-Gide® Perio produces significantly better results than open flap debridement alone. Five-year data show higher clinical attachment level gains and greater pocket depth reduction1.


  1. Sculean A et al., J Clin Periodontol. 2007 Jan;34(1):72-77 (Clinical study). 37
  2. Newman MG, et al., Caranza's Clinical Periodontology. Elsevier (Book).
  3. Lindhe J, et al., Clinical Periodontology and Implant Dentistry. Blackwell Munksgaard (Book).
  4. Rateitschak EM, Wolf HF, Farbatlanten der Zahnmedizin. Band 1: Parodontologie. Thieme (Book)
  5. Perelman-Karmon M et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65. (Clinical study)
  6. Schwarz F et al. Clin. Oral Implants Res. 2006;17(4):403-409. (Pre-clinical study)
  7. Tal H et al. Clin Oral Implants Res. 2008; 19(3) : 295-302. (Clinical study)
  8. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study)
  9. Zitzmann NU et al. Int J Oral Maxillofac Implants.12, 1997;844-852. (Clinical study)
  10. Rothamel D et al. Clin. Oral Implants Res. 2004;15:443-449. (Pre-clinical study)

Clinical Cases

Treatment in the aesthetic area

Case by Dr. Pierpaolo Cortellini
Florence, Italy

Clinical case

Anterior maxillary periodontal regeneration in the aesthetic region: resolving gingival recession and preventing tooth hypermobility.

Geistlich Bio-Oss® and Geistlich Bio-Gide® Perio support re-establishment of full functional attachment.

Treatment in the posterior area

Case by Dr. Diego Capri
Bologna, Italy

Clinical case

Posterior periodontal regeneration: resolving an extended three-wall defect caused by a cemental tear.

Geistlich Bio-Oss® and Geistlich Bio-Gide® Perio help restore soft and hard tissue.

Treatment in the mandibular front area

Case by Prof. Michael Christgau
Dusseldorf, Germany

Clinical case

Anterior mandible periodontal regeneration: resolving an extended two-wall defect.

The combination of Geistlich Bio-Oss® Collagen and Geistlich Bio-Gide® Perio promotes and guides tissue regeneration.