Geistlich Bio-Oss® Collagen

Redefines Bone-Substitute Handling
Geistlich Bio-Oss® Collagen is ideal for Guided Bone Regeneration, particularly for Ridge Preservation after tooth extraction and bone regeneration around implants.

Why Your Patients Will Love the Results
- Fewer follow-up surgeries needed: our bone grafting material offers superior bone preservation compared to spontaneous healing, leading to fewer re-graftings and better esthetic implant options.1 This allows for more options for esthetic prosthetics, such as bridges or prosthetically driven implant placements.
- Flexible timing: volume-stable bone graft allows flexible implant timing based on your patients’ needs.
References:
- Rohner D et al., Int J Oral Maxillofac Surg. 2013 May;42(5):585-91 (Clinical study).
- Trevisiol L et al.: J Craniofac Surg. 2012; 23 (5), 1343-8 (Clinical study).
- iData Research, Market Report Suite for Dental Bone Graft Substitutes and Other Biomaterials (Oct 2021)
- Batas L et al.: Dent J (Basel). 2024 Mar 20;12(3):80 (Clinical study).
- Roccuzzo M et al.: Int J Periodontics Restorative Dent. 2014; 34 (6), 795-804 (Clinical study).
- Araújo MG et al., Clin Oral Implants Res. 2010 Jan;21(1):55-64 (Preclinical study).
- Mordenfeld A et al., Clin. Oral Implant Res. 2010, Sep;21(9):961–70 (Clinical study).
- Junker R & Behring J, J Osseointegr. 2023;15(2):113-123 (Clinical study).

Perform With User Friendly and Time-Saving Products
- Saves time: the added collagen fibers in Geistlich Bio-Oss® Collagen make it easy to cut and mold into defects.2
- Ease of placement: simplified in situ application compared with granules.1
- No pre-wetting mandatory: Geistlich Bio-Oss® Collagen can be used dry to absorb blood, or pre-wetted with saline solution before use.
- Easy-to-use bone substitute block is available in small and large sizes for different bone defect sizes, for instance for Ridge Preservation in anterior and posterior extraction sockets.
References:
- Rohner D et al., Int J Oral Maxillofac Surg. 2013 May;42(5):585-91 (Clinical study).
- Trevisiol L et al.: J Craniofac Surg. 2012; 23 (5), 1343-8 (Clinical study).
- iData Research, Market Report Suite for Dental Bone Graft Substitutes and Other Biomaterials (Oct 2021)
- Batas L et al.: Dent J (Basel). 2024 Mar 20;12(3):80 (Clinical study).
- Roccuzzo M et al.: Int J Periodontics Restorative Dent. 2014; 34 (6), 795-804 (Clinical study).
- Araújo MG et al., Clin Oral Implants Res. 2010 Jan;21(1):55-64 (Preclinical study).
- Mordenfeld A et al., Clin. Oral Implant Res. 2010, Sep;21(9):961–70 (Clinical study).
- Junker R & Behring J, J Osseointegr. 2023;15(2):113-123 (Clinical study).

Exceptional Results You Can Rely On
- Reliability: Geistlich Bio-Oss® granules provide Geistlich Bio-Oss® Collagen with all the advantages of the clinically proven, gold-standard bone substitute material for Guided Bone Regeneration (GBR), leading to predictable exceptional results.3
- Long-term implant success: studies show over seven years of clinical implant success.4,5
- Stable bone volume: the low resorption rate of Geistlich Bio-Oss® Collagen ensures long-term stable bone volume.6-8
References:
- Rohner D et al., Int J Oral Maxillofac Surg. 2013 May;42(5):585-91 (Clinical study).
- Trevisiol L et al.: J Craniofac Surg. 2012; 23 (5), 1343-8 (Clinical study).
- iData Research, Market Report Suite for Dental Bone Graft Substitutes and Other Biomaterials (Oct 2021)
- Batas L et al.: Dent J (Basel). 2024 Mar 20;12(3):80 (Clinical study).
- Roccuzzo M et al.: Int J Periodontics Restorative Dent. 2014; 34 (6), 795-804 (Clinical study).
- Araújo MG et al., Clin Oral Implants Res. 2010 Jan;21(1):55-64 (Preclinical study).
- Mordenfeld A et al., Clin. Oral Implant Res. 2010, Sep;21(9):961–70 (Clinical study).
- Junker R & Behring J, J Osseointegr. 2023;15(2):113-123 (Clinical study).
Redefining Easy Handling of Bone Substitutes
Geistlich Bio-Oss® Collagen was designed with user-friendly handling in mind.
The small amount of collagen improves the handling properties, while the bone substitute material supports effective and reliable bone formation. This makes bone augmentation easier compared to traditional bone substitutes.
Ready To Use
Geistlich Bio-Oss® Collagen is a ready-to-use bone substitute block available in different sizes and suitable for Ridge Preservation, Guided Bone Regeneration around implants and periodontal treatments.
High Hydrophilicity
Geistlich Bio-Oss® Collagen can be applied either dry or after pre-wetting with saline or blood.
Thanks to its high hydrophilicity, it becomes fully wetted within one minute.
Easy To Trim
Geistlich Bio-Oss® Collagen can be trimmed to the desired shape.
Learn more about the L-Shape Technique, which supports optimal bone levels for esthetic implant restorations.
Easy To Mold
In addition to being cut into shape, Geistlich Bio-Oss® Collagen can be molded with fingers or a spatula once pre-wetted.
Easy To Apply
Geistlich Bio-Oss® Collagen holds together for hassle-free application.
Thanks to its ability to be formed easily, it adapts well to the defect once applied.
Excessive compression should be avoided.
Porous with a Purpose
Geistlich Bio-Oss® Collagen features both micro- and macro-pores.
The micro-pores contribute to its high hydrophilicity, allowing the bone graft to absorb nutrients and growth factors.
The macro-pores support the formation of a scaffold for bone-forming cells.
Your Advantages at a Glance
- Ready to use
- Easy to trim
- Highly hydrophilic
- Easy to mold
- Easy to apply
- Porous for bone formation
Geistlich Bio-Oss® Collagen
Redefines Bone-Substitute Handling
You Can’t Cut Corners When Leading Regenerative Dentistry
Our Swiss-made products—like Geistlich Bio-Oss® Collagen—meet the highest quality standards in sourcing, production, and logistics and have undergone rigorous testing in over 1,650 studies worldwide to ensure their safety and efficacy.
Geistlich offers a comprehensive suite of resources for dental professionals. It provides a variety of training and courses, available in multiple formats, covering a wide range of topics, from regeneration biology to effective patient communication. Geistlich also offers patient education materials to help dentists explain treatment options and increase case acceptance rates.
Leading Experts Trust Geistlich Bio-Oss® Collagen
Long-Term Implant Success With Geistlich Bio-Oss® Collagen

Ridge Preservation with Geistlich Bio-Oss® Collagen & Geistlich Mucograft® Seal leads to:
- 100% implant success
- Minimal bone loss
- Pleasing esthetic results
over a period of more than seven years4.
References:
- Rohner D et al., Int J Oral Maxillofac Surg. 2013 May;42(5):585-91 (Clinical study).
- Trevisiol L et al.: J Craniofac Surg. 2012; 23 (5), 1343-8 (Clinical study).
- iData Research, Market Report Suite for Dental Bone Graft Substitutes and Other Biomaterials (Oct 2021)
- Batas L et al.: Dent J (Basel). 2024 Mar 20;12(3):80 (Clinical study).
- Roccuzzo M et al.: Int J Periodontics Restorative Dent. 2014; 34 (6), 795-804 (Clinical study).
- Araújo MG et al., Clin Oral Implants Res. 2010 Jan;21(1):55-64 (Preclinical study).
- Mordenfeld A et al., Clin. Oral Implant Res. 2010, Sep;21(9):961–70 (Clinical study).
- Junker R & Behring J, J Osseointegr. 2023;15(2):113-123 (Clinical study).
Ideal for Ridge Preservation and Guided Bone Regeneration Around Implants
For clinicians who seek exceptional results while balancing valuable time, we provide efficient and proven solutions to achieve clinical and professional success. Geistlich Bio-Oss® Collagen is part of Geistlich’s treatment solutions for Ridge Preservation and Guided Bone Regeneration around implants.

